aa3 gift Search Results


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R&D Systems aa3 gift
Aa3 Gift, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Biogen Inc aa3 mab
Aa3 Mab, supplied by Biogen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Mouse Anti Ifnar1 Aa3 Mab, supplied by Biogen Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell Signaling Technology Inc aa3
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Cell Signaling Technology Inc rat anti plp aa3
Rat Anti Plp Aa3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cell Signaling Technology Inc plp
Plp, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Macklin Inc proteolipid protein (plp; aa3 rat clone) antibody
Representative case of a subject with grossly apparent hyperpigmented thalamic lesions on a 1 cm fixed coronal slice (A); enlarged lesion shown below. Both ovoid (B) and subependymal (C) lesions are noted using PLP immunohistochemistry for myelin; asterisk (*) denotes location of vessel. Magnetic resonance imaging (MRI) coronal images, with thalamus depicted with a white outline, (D) depict fluid-attenuated inversion recovery (FLAIR) and T1-Magnetization Prepared Rapid Acquisition of Gradient Echo (MPRAGE) sequences as well as ovoid (blue) and subependymal (Subep.; green) manually segmented lesions. The heart-shaped hyperpigmented lesion straddling the dorsomedial and ventrolateral nuclei is indicated with an arrow and an enlarged inset of the lesion is below (A). The lesion is demyelinated (B) and labeled as ovoid/perivascular (“Ovoid”) on MRI T1 MPRAGE (D). Subependymal lesions (C) were not identified on gross examination (A) and subtle on MRI (D; labeled “Subep.”). PV, perivascular; PLP, <t>proteolipid</t> protein.
Proteolipid Protein (Plp; Aa3 Rat Clone) Antibody, supplied by Macklin Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Macklin Inc rat anti-plp1
Representative case of a subject with grossly apparent hyperpigmented thalamic lesions on a 1 cm fixed coronal slice (A); enlarged lesion shown below. Both ovoid (B) and subependymal (C) lesions are noted using PLP immunohistochemistry for myelin; asterisk (*) denotes location of vessel. Magnetic resonance imaging (MRI) coronal images, with thalamus depicted with a white outline, (D) depict fluid-attenuated inversion recovery (FLAIR) and T1-Magnetization Prepared Rapid Acquisition of Gradient Echo (MPRAGE) sequences as well as ovoid (blue) and subependymal (Subep.; green) manually segmented lesions. The heart-shaped hyperpigmented lesion straddling the dorsomedial and ventrolateral nuclei is indicated with an arrow and an enlarged inset of the lesion is below (A). The lesion is demyelinated (B) and labeled as ovoid/perivascular (“Ovoid”) on MRI T1 MPRAGE (D). Subependymal lesions (C) were not identified on gross examination (A) and subtle on MRI (D; labeled “Subep.”). PV, perivascular; PLP, <t>proteolipid</t> protein.
Rat Anti Plp1, supplied by Macklin Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Millipore anti-ng2
Representative case of a subject with grossly apparent hyperpigmented thalamic lesions on a 1 cm fixed coronal slice (A); enlarged lesion shown below. Both ovoid (B) and subependymal (C) lesions are noted using PLP immunohistochemistry for myelin; asterisk (*) denotes location of vessel. Magnetic resonance imaging (MRI) coronal images, with thalamus depicted with a white outline, (D) depict fluid-attenuated inversion recovery (FLAIR) and T1-Magnetization Prepared Rapid Acquisition of Gradient Echo (MPRAGE) sequences as well as ovoid (blue) and subependymal (Subep.; green) manually segmented lesions. The heart-shaped hyperpigmented lesion straddling the dorsomedial and ventrolateral nuclei is indicated with an arrow and an enlarged inset of the lesion is below (A). The lesion is demyelinated (B) and labeled as ovoid/perivascular (“Ovoid”) on MRI T1 MPRAGE (D). Subependymal lesions (C) were not identified on gross examination (A) and subtle on MRI (D; labeled “Subep.”). PV, perivascular; PLP, <t>proteolipid</t> protein.
Anti Ng2, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Representative case of a subject with grossly apparent hyperpigmented thalamic lesions on a 1 cm fixed coronal slice (A); enlarged lesion shown below. Both ovoid (B) and subependymal (C) lesions are noted using PLP immunohistochemistry for myelin; asterisk (*) denotes location of vessel. Magnetic resonance imaging (MRI) coronal images, with thalamus depicted with a white outline, (D) depict fluid-attenuated inversion recovery (FLAIR) and T1-Magnetization Prepared Rapid Acquisition of Gradient Echo (MPRAGE) sequences as well as ovoid (blue) and subependymal (Subep.; green) manually segmented lesions. The heart-shaped hyperpigmented lesion straddling the dorsomedial and ventrolateral nuclei is indicated with an arrow and an enlarged inset of the lesion is below (A). The lesion is demyelinated (B) and labeled as ovoid/perivascular (“Ovoid”) on MRI T1 MPRAGE (D). Subependymal lesions (C) were not identified on gross examination (A) and subtle on MRI (D; labeled “Subep.”). PV, perivascular; PLP, proteolipid protein.

Journal: Annals of neurology

Article Title: Intrinsic and Extrinsic Mechanisms of Thalamic Pathology in Multiple Sclerosis

doi: 10.1002/ana.25743

Figure Lengend Snippet: Representative case of a subject with grossly apparent hyperpigmented thalamic lesions on a 1 cm fixed coronal slice (A); enlarged lesion shown below. Both ovoid (B) and subependymal (C) lesions are noted using PLP immunohistochemistry for myelin; asterisk (*) denotes location of vessel. Magnetic resonance imaging (MRI) coronal images, with thalamus depicted with a white outline, (D) depict fluid-attenuated inversion recovery (FLAIR) and T1-Magnetization Prepared Rapid Acquisition of Gradient Echo (MPRAGE) sequences as well as ovoid (blue) and subependymal (Subep.; green) manually segmented lesions. The heart-shaped hyperpigmented lesion straddling the dorsomedial and ventrolateral nuclei is indicated with an arrow and an enlarged inset of the lesion is below (A). The lesion is demyelinated (B) and labeled as ovoid/perivascular (“Ovoid”) on MRI T1 MPRAGE (D). Subependymal lesions (C) were not identified on gross examination (A) and subtle on MRI (D; labeled “Subep.”). PV, perivascular; PLP, proteolipid protein.

Article Snippet: Primary antibodies included: proteolipid protein (PLP; AA3 rat clone, a gift from Wendy Macklin, University of Denver, CO, 1:250 dilution) for myelin, HuR (Santa Cruz Biotechnology, Dallas, TX, mouse IgG, SC-5261, 3A2 clone, 1:500 dilution) for neurons, major histocompatibility complex class II (MHCII, HLA-DR CR3/43, Dako, Santa Clara, CA, mouse monoclonal, M0775, 1:500 dilution) for activated microglia, and SMI31 (mouse IgG1k, Biolegend, San Diego, CA, 801601, 1:2500 dilution) and SMI32 (mouse monoclonal, Biolegend, 801701, 1:2500 dilution) for axons and dendrites.

Techniques: Immunohistochemistry, Magnetic Resonance Imaging, Labeling

Patterns of thalamic lesions characterized by immunohistochemistochemical staining for myelin (PLP) and activated microglia/macrophages (MHCII). Lesions top to bottom: chronic inactive (hypocellular center with asterisk*), chronic active (rim of hypercellularity; vessels labeled with “V”), active (hypercellular), and subependymal (Subep.) demyelination, areas of perivascular inflammation without demyelination (vessels labeled “>”). Scale bars are 3 mm for all images except for “PV inflammation” (600 μm). MHC, major histocompatibility complex; NAGM, normal appearing grey matter; PLP, proteolipid protein; PV, perivascular.

Journal: Annals of neurology

Article Title: Intrinsic and Extrinsic Mechanisms of Thalamic Pathology in Multiple Sclerosis

doi: 10.1002/ana.25743

Figure Lengend Snippet: Patterns of thalamic lesions characterized by immunohistochemistochemical staining for myelin (PLP) and activated microglia/macrophages (MHCII). Lesions top to bottom: chronic inactive (hypocellular center with asterisk*), chronic active (rim of hypercellularity; vessels labeled with “V”), active (hypercellular), and subependymal (Subep.) demyelination, areas of perivascular inflammation without demyelination (vessels labeled “>”). Scale bars are 3 mm for all images except for “PV inflammation” (600 μm). MHC, major histocompatibility complex; NAGM, normal appearing grey matter; PLP, proteolipid protein; PV, perivascular.

Article Snippet: Primary antibodies included: proteolipid protein (PLP; AA3 rat clone, a gift from Wendy Macklin, University of Denver, CO, 1:250 dilution) for myelin, HuR (Santa Cruz Biotechnology, Dallas, TX, mouse IgG, SC-5261, 3A2 clone, 1:500 dilution) for neurons, major histocompatibility complex class II (MHCII, HLA-DR CR3/43, Dako, Santa Clara, CA, mouse monoclonal, M0775, 1:500 dilution) for activated microglia, and SMI31 (mouse IgG1k, Biolegend, San Diego, CA, 801601, 1:2500 dilution) and SMI32 (mouse monoclonal, Biolegend, 801701, 1:2500 dilution) for axons and dendrites.

Techniques: Staining, Labeling, Immunopeptidomics